Phospho-PKR/EIF2AK2-T446 Rabbit mAb

Catalog Number:

78116

Amount:

100μg

Price:

$318

Swiss-Prot No:

P19525

Form of Antibody:

Storage/Stability:

Immunogen:

A phospho specific peptide corresponding to residues surrounding T446 of human PKR/EIF2AK2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF