ACE1 Rabbit mAb

Catalog Number:

77952

Amount:

100μg

Price:

$318

Swiss-Prot No:

P12821

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human ACE1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB, IP

Background:

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:50 - 1:200

Datasheet PDF