1-832-868-1888
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Catalog Number: |
77781 |
other_names: | HFE; HFE1; HH; HLA-H; MVCD7; TFQTL2; hemochromatosis |
Amount: |
100μg |
calculated_mw: | 40kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
Q30201 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human HFE. |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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