CD11a/LFA-1A/ITGAL Rabbit mAb

Catalog Number:

77771

Amount:

100μg

Price:

$318

Swiss-Prot No:

P20701

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CD11a/LFA-1A/ITGAL

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF