PARP1 Mouse mAb

Catalog Number:

77762

Amount:

100μg

Price:

$318

Swiss-Prot No:

P09874

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human PARP1.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF