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Caveolin-3 Rabbit mAb

Catalog Number:

77685
other_names: LGMD1C, LQT9, VIP-21, VIP21

Amount:

100μg
calculated_mw: 17kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P56539

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Caveolin-3

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

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