FKBP51/FKBP5 Rabbit mAb

Catalog Number:

77578

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q13451

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human FKBP51/FKBP5

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF