1-832-206-4069
order@swbio.com
catalog number: |
77524 |
other_names: | sir2, sir2l, sir2l2 |
amount: |
100μg |
calculated_mw: | 36kda |
host_species: | rabbit |
price: |
$318 |
swiss-prot no: |
q8ixj6 |
form of antibody: |
|
storage/stability: |
|
immunogen: |
a synthesized peptide derived from human sirt2 |
purification: |
affinity purification |
specificity/sensitivity: |
|
applications: |
wb |
background: |
this gene encodes a member of the sirtuin family of proteins, homologs to the yeast sir2 protein. members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. the functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rdna. studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-adp-ribosyltransferase activity. the protein encoded by this gene is included in class i of the sirtuin family. several transcript variants are resulted from alternative splicing of this gene. [provided by refseq, jul 2010] |
references: |
|
appl_detail: |
wb 1:500 - 1:2000 |
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