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Caspase-2 Rabbit mAb

Catalog Number:

77478
other_names: CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57

Amount:

100μg
calculated_mw: 12kDa/30kDa/48kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P42575

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Caspase-2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

References:

appl_detail:

WB 1:500 - 1:2000

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