1-832-868-1888
order@swbio.com
Catalog Number: |
77478 |
other_names: | CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57 |
Amount: |
100μg |
calculated_mw: | 12kDa/30kDa/48kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P42575 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human Caspase-2 |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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