ABCG2 Rabbit mAb

Catalog Number:

77472

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q9UNQ0

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human ABCG2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF