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Catalog Number: |
77437 |
other_names: | UBE2B; E2-17kDa; HHR6B; HR6B; RAD6B; UBC2; ubiquitin-conjugating enzyme E2 B |
Amount: |
100μg |
calculated_mw: | 17kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P63146 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human UBE2B. |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC |
Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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