1-832-868-1888
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Catalog Number: |
77432 |
other_names: | ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I |
Amount: |
100μg |
calculated_mw: | 56kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P37023 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human ACVRL1 |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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