SHP2 Rabbit mAb

Catalog Number:

77424

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q06124

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human SHP2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF,IP

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF