PLC gamma 2 (PLCG2) Rabbit mAb

Catalog Number:

77376

Amount:

100μg

Price:

$318

Swiss-Prot No:

P16885

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human PLC gamma 2 (PLC gamma 2 (PLCG2))

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF