HP1 alpha/CBX5 Rabbit mAb

Catalog Number:

77368

Amount:

100μg

Price:

$318

Swiss-Prot No:

P45973

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human HP1 alpha/CBX5

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF,IP

Background:

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF