PCNA Rabbit mAb

Catalog Number:

77357

Amount:

100μg

Price:

$318

Swiss-Prot No:

P12004

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human PCNA

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IP

Background:

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF