Dopamine Receptor D3 (DRD3) Rabbit mAb

Catalog Number:

77068

Amount:

100μg

Price:

$318

Swiss-Prot No:

P35462

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Dopamine Receptor D3 (DRD3) (DRD3)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF