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RAIDD/CRADD Rabbit mAb

Catalog Number:

77028
other_names: MRT34, RAIDD

Amount:

100μg
calculated_mw: 23kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P78560

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human RAIDD/CRADD

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

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