1-832-868-1888
order@swbio.com
Catalog Number: |
77028 |
other_names: | MRT34, RAIDD |
Amount: |
100μg |
calculated_mw: | 23kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P78560 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human RAIDD/CRADD |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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