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Home > products > Histone H2B(mono methyl R79) Antibody

Histone H2B(mono methyl R79) Antibody

Catalog Number:

HW229
other_names: H2B 1A antibody
H2B antibody
H2B histone family antibody
H2B2f antibody
H2B2F_HUMAN antibody
H2Ba antibody
H2Bf antibody
HIST2H2BF antibody
histone H2B antibody
histone H2B type 1 antibody
Histone H2B type 2-F antibody
MGC131639 antibody

Amount:

100μg
calculated_mw: 14 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60814

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC/IF, IHC

Background:

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

References:

appl_detail:

WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

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