Histone H3 (tri methyl K9) Antibody

Catalog Number:

HW217

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P68431

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Amino acids 6-16 of Histone H3 trimethylated at Lysine 9 of human origin.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, IF

Background:

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Human Histone H3 is subject to trimethylation at Lys 9, a modification that may be necessary for select DNA transactions or chromatin state transitions.

References:

appl_detail:

WB: 1:100-1:1,000

 

Datasheet PDF