Histone H4K20me3 Polyclonal Antibody

Catalog Number:

HW033

Amount:

100μg

Price:

$319

Swiss-Prot No:

Gene ID: 8290 Swiss Prot: Q16695

Form of Antibody:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4

Purification:

Antibodies were produced by immunizing rabbits and were purified by antigen affinity-chromatography.

Specificity/Sensitivity:

Applications:

WB IF IP ChIP

Background:

 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

References:

appl_detail:

WB 1:500 - 1:2000

IF 1:50 - 1:200

IP 1:50 - 1:200

CHIP 1:50 - 1:100

Datasheet PDF